top of page

Insights for a Healthier, Longer Life
All Posts


Galleri: The Cancer Test Everyone Is Talking About
Let’s start with some good news: cancer death rates in the United States are falling . Since 1991, the age-adjusted cancer mortality...
Ali Zaidi
Oct 13 min read


Do you know your polygenic risk score for heart disease?
TLDR: Polygenic risk scores estimate risk by summing thousands of small genetic effects. For heart disease, high PRS can reveal hidden...
Ali Zaidi
Oct 14 min read


The Rosetto Effect
In the 1950’s, physicians in the small Italian immigrant town of Roseto, Pennsylvania made a remarkable observation: residents of Roseto...
Ali Zaidi
Aug 274 min read


Why skinny fat is bad for you
A friend recently asked: “I’m South Asian and people say I’m ‘skinny fat.’ What is that—and how can I prevent it?” That question echoes...
Ali Zaidi
Aug 275 min read


Before the Sugar Spikes: Can Insulin Levels Predict Diabetes?
Biomarker testing has become increasingly popular. Companies like Function Health , Healthspan , Superpower and others offer a wide...
Ali Zaidi
Jul 233 min read


The strongest predictor of mortality that your doctor doesn't measure
Why you should know your VO2 max In medicine, one of our core responsibilities is to assess your risk for disease, so we can take steps...
Ali Zaidi
Jul 233 min read


Do statins increase your risk of dementia
I had lunch with a friend recently whose mother has dementia. My friend takes a statin to lower her risk of cardiovascular disease, but...
Ali Zaidi
Jul 73 min read


Why I'm aggressive about my cholesterol
Cholesterol deposition in an artery As I mentioned in my last post , I decided to lower my cholesterol even with a calcium score of zero....
Ali Zaidi
Jul 73 min read


Should I get a Coronary Artery Calcium Test?
The other day a friend of mine asked me if he should get a coronary artery calcium (CAC) test. He is a healthy man in his 40’s without...
Ali Zaidi
Jun 114 min read


Are we too obsessed about protein?
First, we were told to cut back on fat. Then the spotlight shifted to carbs. Now, the latest nutritional obsession seems to be protein —...
Ali Zaidi
Jun 913 min read


Should I take a supplement?
As a physician who is proactive and data-driven about health, this is one of the most common questions I get asked. My response is going...
Ali Zaidi
Jun 96 min read
bottom of page