Insights for a Healthier, Longer Life

Let’s start with some good news: cancer death rates in the United States are falling . Since 1991, the age-adjusted cancer mortality...

TLDR: Polygenic risk scores estimate risk by summing thousands of small genetic effects. For heart disease, high PRS can reveal hidden...

In the 1950’s, physicians in the small Italian immigrant town of Roseto, Pennsylvania made a remarkable observation: residents of Roseto...

A friend recently asked: “I’m South Asian and people say I’m ‘skinny fat.’ What is that—and how can I prevent it?” That question echoes...

Biomarker testing has become increasingly popular. Companies like Function Health , Healthspan , Superpower and others offer a wide...

Why you should know your VO2 max In medicine, one of our core responsibilities is to assess your risk for disease, so we can take steps...

I had lunch with a friend recently whose mother has dementia. My friend takes a statin to lower her risk of cardiovascular disease, but...

Cholesterol deposition in an artery As I mentioned in my last post , I decided to lower my cholesterol even with a calcium score of zero....

The other day a friend of mine asked me if he should get a coronary artery calcium (CAC) test. He is a healthy man in his 40’s without...

First, we were told to cut back on fat. Then the spotlight shifted to carbs. Now, the latest nutritional obsession seems to be protein —...

As a physician who is proactive and data-driven about health, this is one of the most common questions I get asked. My response is going...